Endometrial or Uterine Cancer

Endometrial cancer of the uterus, sometimes referred to as uterine cancer, is the most common cancer of the reproductive system. It develops in the uterus, though most endometrial cancers develop in the endometrial glands that line the inner wall of the uterine cavity, rather than in the uterus’ muscular wall.

Signs and Symptoms

Although endometrial cancer usually occurs after menopause, it also may occur around the time that menopause begins. Abnormal vaginal bleeding is the most common symptom of uterine cancer. Bleeding may start as a watery, blood-streaked flow that gradually contains more blood. Women should not assume that abnormal vaginal bleeding is part of menopause.

You should see your doctor if you have any of the following symptoms:

  • Unusual vaginal bleeding or discharge
  • Difficult or painful urination
  • Pain during intercourse
  • Pain in the pelvic area
Reviewed by health care specialists at UCSF Medical Center.